人 SYK (NM_001174167) cDNA克隆

基本信息

Accession: NM_001174167
基因名称: SYK
基因别名: p72-Syk
基因描述: Homo sapiens spleen tyrosine kinase (SYK), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1908 (查看编码区序列)
翻译后氨基酸长度: 635 (查看氨基酸序列)
Transcript Variant: This variant (3) contains an alternate 5' terminal exon compared to variant 1, which introduces an upstream open reading frame (uORF) with a weak Kozak signal, making translation of the downstream primary ORF (with a strong Kozak signal) encoding isoform 1 likely by leaky scanning or re-initiation. Variants 1 and 3 encode the same isoform.

订购信息

产品编号 产品名称 载体 规格 价格
G102374 人 SYK (NM_001174167) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SYK (NM_003177) cDNA克隆 transcript variant 1
人 SYK (NM_001135052) cDNA克隆 transcript variant 2
人 SYK (NM_001174167) cDNA克隆 transcript variant 3
人 SYK (NM_001174168) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

相关产品