人 SPHK2 (NM_001204158) cDNA克隆

基本信息

Accession: NM_001204158
基因名称: SPHK2
基因别名: SK 2; SK-2; SPK 2; SPK-2
基因描述: Homo sapiens sphingosine kinase 2 (SPHK2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1788 (查看编码区序列)
翻译后氨基酸长度: 595 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G102397 人 SPHK2 (NM_001204158) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SPHK2 (NM_020126) cDNA克隆 transcript variant 1
人 SPHK2 (NM_001204158) cDNA克隆 transcript variant 2
人 SPHK2 (NM_001204159) cDNA克隆 transcript variant 3
人 SPHK2 (NM_001204160) cDNA克隆 transcript variant 4
人 SPHK2 (NM_001243876) cDNA克隆 transcript variant 5

基因简介

This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

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