人 UQCRB (NM_001199975) cDNA克隆

基本信息

Accession: NM_001199975
基因名称: UQCRB
基因别名: QPC; QCR7; QP-C; UQBC; UQBP; UQPC; UQCR6; MC3DN3
基因描述: Homo sapiens ubiquinol-cytochrome c reductase binding protein (UQCRB), transcript variant 2, mRNA.
种属: Human
CDS区长度: 240 (查看编码区序列)
翻译后氨基酸长度: 79 (查看氨基酸序列)
Transcript Variant: This variant (2) has an additional exon in its 5' UTR, which results in the use of a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G102923 人 UQCRB (NM_001199975) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 UQCRB (NM_006294) cDNA克隆 transcript variant 1
人 UQCRB (NM_001199975) cDNA克隆 transcript variant 2
人 UQCRB (NM_001254752) cDNA克隆 transcript variant 3

基因简介

This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X. [provided by RefSeq, Dec 2011]

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