人 GGCT (NM_001199817) cDNA克隆

Accession: NM_001199817
基因名称: GGCT
基因别名: GGC; GCTG; CRF21; C7orf24
基因描述: Homo sapiens gamma-glutamylcyclotransferase (GGCT), transcript variant 4, mRNA.
种属: Human
CDS区长度: 285 (查看编码区序列)
翻译后氨基酸长度: 94 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks multiple exons in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 4, which is shorter than isoform 1.
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G102937 人 GGCT (NM_001199817) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]