人 SAA1 (NM_000331) cDNA克隆

Accession: NM_000331
基因名称: SAA1
基因别名: SAA; PIG4; SAA2; TP53I4
基因描述: Homo sapiens serum amyloid A1 (SAA1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 369 (查看编码区序列)
翻译后氨基酸长度: 122 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
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G102969 人 SAA1 (NM_000331) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Jun 2012]