Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]
人 GNB5 (NM_016194) cDNA克隆
| Accession: | NM_016194 |
|---|---|
| 基因名称: | GNB5 |
| 基因别名: | GB5 |
| 基因描述: | Homo sapiens guanine nucleotide binding protein (G protein), beta 5 (GNB5), transcript variant 2, mRNA. |
| 种属: | Human |
| CDS区长度: | 1188 (查看编码区序列) |
| 翻译后氨基酸长度: | 395 (查看氨基酸序列) |
| Transcript Variant: | This variant (2) has two additional exons at its 5' end, but lacks the 5' portion of its third exon, compared to variant 1. It encodes an isoform (b) containing 42 additional amino acids at its N terminus compared to isoform a. This isoform is also referred to as beta subunit 5L. |
| 人 GNB5 (NM_006578) cDNA克隆 | transcript variant 1 |
| 人 GNB5 (NM_016194) cDNA克隆 | transcript variant 2 |
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