人 MST4 (NM_001042452) cDNA克隆

基本信息

Accession: NM_001042452
基因名称: MST4
基因别名: MASK
基因描述: Homo sapiens serine/threonine protein kinase MST4 (MST4), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1065 (查看编码区序列)
翻译后氨基酸长度: 354 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon, compared to variant 1. The resulting isoform (3) is shorter compared to isoform 1, and lacks kinase activity.

订购信息

产品编号 产品名称 载体 规格 价格
G103061 人 MST4 (NM_001042452) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MST4 (NM_016542) cDNA克隆 transcript variant 1
人 MST4 (NM_001042453) cDNA克隆 transcript variant 2
人 MST4 (NM_001042452) cDNA克隆 transcript variant 3

基因简介

The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

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