人 TSC22D1 (NM_001243797) cDNA克隆

基本信息

Accession: NM_001243797
基因名称: TSC22D1
基因别名: Ptg-2; TSC22; TGFB1I4
基因描述: Homo sapiens TSC22 domain family, member 1 (TSC22D1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 261 (查看编码区序列)
翻译后氨基酸长度: 86 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a large portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. Variants 3 and 4 encode the same isoform (3), which has a significantly shorter N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G103099 人 TSC22D1 (NM_001243797) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TSC22D1 (NM_183422) cDNA克隆 transcript variant 1
人 TSC22D1 (NM_006022) cDNA克隆 transcript variant 2
人 TSC22D1 (NM_001243797) cDNA克隆 transcript variant 3
人 TSC22D1 (NM_001243798) cDNA克隆 transcript variant 4
人 TSC22D1 (NM_001243799) cDNA克隆 transcript variant 5

基因简介

This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

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