人 SRSF10 (NM_001191009) cDNA克隆

Accession: NM_001191009
基因名称: SRSF10
基因别名: NSSR; TASR; SRp38; TASR1; TASR2; FUSIP1; FUSIP2; SFRS13; SRrp40; SFRS13A
基因描述: Homo sapiens serine/arginine-rich splicing factor 10 (SRSF10), transcript variant 6, mRNA.
种属: Human
CDS区长度: 498 (查看编码区序列)
翻译后氨基酸长度: 165 (查看氨基酸序列)
Transcript Variant: This variant (6) lacks an in-frame exon in the 3' coding region and uses a distinct exon for its 3' terminus, compared to variant 2. These differences result in an isoform (6) with a shorter and distinct C-terminus that lacks an SR domain, compared to isoform 2.
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G103257 人 SRSF10 (NM_001191009) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. This gene has multiple pseudogenes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.[provided by RefSeq, Jul 2010]