人 CASC4 (NM_177974) cDNA克隆

Accession: NM_177974
基因名称: CASC4
基因别名: H63
基因描述: Homo sapiens cancer susceptibility candidate 4 (CASC4), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1143 (查看编码区序列)
翻译后氨基酸长度: 380 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (b), that is missing an internal segment compared to isoform a.
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G103273 人 CASC4 (NM_177974) cDNA克隆 pDONR223 2ug质粒 点击询价

The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]