TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]).[supplied by OMIM, Nov 2010]
Accession: | NM_001031800 |
---|---|
基因名称: | TIPRL |
基因别名: | TIP; TIP41 |
基因描述: | Homo sapiens TIP41, TOR signaling pathway regulator-like (S. cerevisiae) (TIPRL), transcript variant 2, mRNA. |
种属: | Human |
CDS区长度: | 537 (查看编码区序列) |
翻译后氨基酸长度: | 178 (查看氨基酸序列) |
Transcript Variant: | This variant (2) lacks several exons, and uses an alternate 3'-terminal exon, compared to variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. |
人 TIPRL (NM_152902) cDNA克隆 | transcript variant 1 |
人 TIPRL (NM_001031800) cDNA克隆 | transcript variant 2 |
TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]).[supplied by OMIM, Nov 2010]