人 RHOH (NM_001278365) cDNA克隆

基本信息

Accession: NM_001278365
基因名称: RHOH
基因别名: TTF; ARHH
基因描述: Homo sapiens ras homolog family member H (RHOH), transcript variant 8, mRNA.
种属: Human
CDS区长度: 576 (查看编码区序列)
翻译后氨基酸长度: 191 (查看氨基酸序列)
Transcript Variant: This variant (8) differs in the 5' most exons and lacks an exon in the 5' UTR, compared to variant 1. Variants 1 through 12 encode the same protein.

订购信息

产品编号 产品名称 载体 规格 价格
G103348 人 RHOH (NM_001278365) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RHOH (NM_001278359) cDNA克隆 transcript variant 1
人 RHOH (NM_001278367) cDNA克隆 transcript variant 10
人 RHOH (NM_001278368) cDNA克隆 transcript variant 11
人 RHOH (NM_001278369) cDNA克隆 transcript variant 12
人 RHOH (NM_001278360) cDNA克隆 transcript variant 2
人 RHOH (NM_001278361) cDNA克隆 transcript variant 3
人 RHOH (NM_001278362) cDNA克隆 transcript variant 4
人 RHOH (NM_001278363) cDNA克隆 transcript variant 5
人 RHOH (NM_004310) cDNA克隆 transcript variant 6
人 RHOH (NM_001278364) cDNA克隆 transcript variant 7
人 RHOH (NM_001278365) cDNA克隆 transcript variant 8
人 RHOH (NM_001278366) cDNA克隆 transcript variant 9

基因简介

The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]

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