人 COPS8 (NM_198189) cDNA克隆

基本信息

Accession: NM_198189
基因名称: COPS8
基因别名: COP9; CSN8; SGN8
基因描述: Homo sapiens COP9 signalosome subunit 8 (COPS8), transcript variant 2, mRNA.
种属: Human
CDS区长度: 483 (查看编码区序列)
翻译后氨基酸长度: 160 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an additional exon compared to variant 1, resulting in translation initiation from a downstream start codon and an isoform (2) with a shorter N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G103439 人 COPS8 (NM_198189) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 COPS8 (NM_006710) cDNA克隆 transcript variant 1
人 COPS8 (NM_198189) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

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