人 APOL1 (NM_003661) cDNA克隆

Accession: NM_003661
基因名称: APOL1
基因别名: APOL; APO-L; FSGS4; APOL-I
基因描述: Homo sapiens apolipoprotein L, 1 (APOL1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1197 (查看编码区序列)
翻译后氨基酸长度: 398 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the predominant protein (isoform a). Variants 1 and 3 encode the same protein (isoform a).
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G103599 人 APOL1 (NM_003661) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]