人 HMOX2 (NM_001127204) cDNA克隆

Accession: NM_001127204
基因名称: HMOX2
基因别名: HO-2
基因描述: Homo sapiens heme oxygenase (decycling) 2 (HMOX2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 951 (查看编码区序列)
翻译后氨基酸长度: 316 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR and coding sequence compared to variant 5. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 1, 2, 3, 4, 6, 7, and 8 all encode the same isoform (b).
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G103816 人 HMOX2 (NM_001127204) cDNA克隆 pDONR223 2ug质粒 点击询价

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]