人 ADRM1 (NM_007002) cDNA克隆

Accession: NM_007002
基因名称: ADRM1
基因别名: ARM1; ARM-1; GP110
基因描述: Homo sapiens adhesion regulating molecule 1 (ADRM1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1224 (查看编码区序列)
翻译后氨基酸长度: 407 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1 and 2 encode the same isoform.
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G103930 人 ADRM1 (NM_007002) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]