人 NOSTRIN (NM_052946) cDNA克隆

基本信息

Accession: NM_052946
基因名称: NOSTRIN
基因别名: DaIP2
基因描述: Homo sapiens nitric oxide synthase trafficking (NOSTRIN), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1287 (查看编码区序列)
翻译后氨基酸长度: 428 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks an internal exon in the 5' region, resulting in a downstream AUG start codon, as compared to isoform 2. The resulting isoform (1) has a shorter N-terminus, as compared to isoform 2.

订购信息

产品编号 产品名称 载体 规格 价格
G103962 人 NOSTRIN (NM_052946) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NOSTRIN (NM_052946) cDNA克隆 transcript variant 1
人 NOSTRIN (NM_001039724) cDNA克隆 transcript variant 2
人 NOSTRIN (NM_001171632) cDNA克隆 transcript variant 3
人 NOSTRIN (NM_001171631) cDNA克隆 transcript variant 4

基因简介

Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004]

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