人 PORCN (NM_022825) cDNA克隆

基本信息

Accession: NM_022825
基因名称: PORCN
基因别名: PPN; DHOF; FODH; MG61; PORC
基因描述: Homo sapiens porcupine homolog (Drosophila) (PORCN), transcript variant A, mRNA.
种属: Human
CDS区长度: 1353 (查看编码区序列)
翻译后氨基酸长度: 450 (查看氨基酸序列)
Transcript Variant: This variant (A) lacks two in-frame exons in the central coding region, compared to variant D. The resulting isoform (A) is shorter, compared to isoform D.

订购信息

产品编号 产品名称 载体 规格 价格
G103988 人 PORCN (NM_022825) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PORCN (NM_022825) cDNA克隆 transcript variant A
人 PORCN (NM_203473) cDNA克隆 transcript variant B
人 PORCN (NM_203474) cDNA克隆 transcript variant C
人 PORCN (NM_203475) cDNA克隆 transcript variant D
人 PORCN (NM_001282167) cDNA克隆 transcript variant F

基因简介

This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2013]

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