人 PVRL2 (NM_002856) cDNA克隆

基本信息

Accession: NM_002856
基因名称: PVRL2
基因别名: HVEB; PRR2; CD112; PVRR2
基因描述: Homo sapiens poliovirus receptor-related 2 (herpesvirus entry mediator B) (PVRL2), transcript variant alpha, mRNA.
种属: Human
CDS区长度: 1440 (查看编码区序列)
翻译后氨基酸长度: 479 (查看氨基酸序列)
Transcript Variant: This variant (alpha) has multiple differences in the coding region, compared to variant delta, one of which results in an early stop codon. The resulting protein (isoform alpha) has a distinct C-terminus and is shorter than isoform delta.

订购信息

产品编号 产品名称 载体 规格 价格
G104017 人 PVRL2 (NM_002856) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PVRL2 (NM_002856) cDNA克隆 transcript variant alpha
人 PVRL2 (NM_001042724) cDNA克隆 transcript variant delta

基因简介

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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