人 MEN1 (NM_130803) cDNA克隆

基本信息

Accession: NM_130803
基因名称: MEN1
基因别名: MEAI; SCG2
基因描述: Homo sapiens multiple endocrine neoplasia I (MEN1), transcript variant e1E, mRNA.
种属: Human
CDS区长度: 1848 (查看编码区序列)
翻译后氨基酸长度: 615 (查看氨基酸序列)
Transcript Variant: This variant (e1E) encodes the same isoform as variant 1. This variant has a distinct 5' UTR from variant 1, but shares some 5' UTR sequence with variant e1F1.

订购信息

产品编号 产品名称 载体 规格 价格
G104130 人 MEN1 (NM_130803) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MEN1 (NM_000244) cDNA克隆 transcript variant 1
人 MEN1 (NM_130799) cDNA克隆 transcript variant 2
人 MEN1 (NM_130800) cDNA克隆 transcript variant e1B
人 MEN1 (NM_130801) cDNA克隆 transcript variant e1C
人 MEN1 (NM_130802) cDNA克隆 transcript variant e1D
人 MEN1 (NM_130803) cDNA克隆 transcript variant e1E
人 MEN1 (NM_130804) cDNA克隆 transcript variant e1F1

基因简介

This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

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