人 EDEM2 (NM_018217) cDNA克隆

Accession: NM_018217
基因名称: EDEM2
基因别名: C20orf31; C20orf49; bA4204.1
基因描述: Homo sapiens ER degradation enhancer, mannosidase alpha-like 2 (EDEM2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1737 (查看编码区序列)
翻译后氨基酸长度: 578 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (1).
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G104140 人 EDEM2 (NM_018217) cDNA克隆 pDONR223 2ug质粒 点击询价

In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008]