人 KARS (NM_005548) cDNA克隆

基本信息

Accession: NM_005548
基因名称: KARS
基因别名: KRS; KARS1; KARS2; CMTRIB; DFNB89
基因描述: Homo sapiens lysyl-tRNA synthetase (KARS), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1794 (查看编码区序列)
翻译后氨基酸长度: 597 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an internal exon in the 5' region, which results in an upstream AUG start codon, as compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G104165 人 KARS (NM_005548) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 KARS (NM_001130089) cDNA克隆 transcript variant 1
人 KARS (NM_005548) cDNA克隆 transcript variant 2

基因简介

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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