人 ITIH5 (NM_001001851) cDNA克隆

Accession: NM_001001851
基因名称: ITIH5
基因别名: ITI-HC5; PP14776
基因描述: Homo sapiens inter-alpha-trypsin inhibitor heavy chain family, member 5 (ITIH5), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2109 (查看编码区序列)
翻译后氨基酸长度: 702 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks several 3' exons and has an alternate 3' exon, compared to variant 1. The encoded isoform (3) has an alternate and shorter C-terminus, compared to isoform 1.
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G104322 人 ITIH5 (NM_001001851) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]