人 TAF1C (NM_001243160) cDNA克隆

Accession: NM_001243160
基因名称: TAF1C
基因别名: SL1; TAFI95; TAFI110; MGC:39976
基因描述: Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa (TAF1C), transcript variant 7, mRNA.
种属: Human
CDS区长度: 1179 (查看编码区序列)
翻译后氨基酸长度: 392 (查看氨基酸序列)
Transcript Variant: This variant (7) differs in several regions and has a downstream AUG start codon, compared to variant 1. The resulting isoform (6) is much shorter at the N-terminus and lacks an internal amino acid 'G', compared to isoform 1.
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G104407 人 TAF1C (NM_001243160) cDNA克隆 pDONR223 2ug质粒 点击询价

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]