人 SMTN (NM_006932) cDNA克隆

基本信息

Accession: NM_006932
基因名称: SMTN
基因描述: Homo sapiens smoothelin (SMTN), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2754 (查看编码区序列)
翻译后氨基酸长度: 917 (查看氨基酸序列)
Transcript Variant: This variant (3) has an alternate 5' exon, which results in a downstream AUG start codon, and lacks an in-frame exon in the middle region, compared to variant 4. The resulting isoform (c, also referred to as L1, B and c1) is shorter at the N-terminus and lacks an internal segment, compared to isoform d. This isoform is highly expressed in all vascularized organs and represents a vascular smooth muscle-specific form. This transcript also includes an alternate downstream translation initiation site, which results in the smoothelin-A product, a visceral smooth muscle-specific form.

订购信息

产品编号 产品名称 载体 规格 价格
G104542 人 SMTN (NM_006932) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SMTN (NM_134270) cDNA克隆 transcript variant 1
人 SMTN (NM_134269) cDNA克隆 transcript variant 2
人 SMTN (NM_006932) cDNA克隆 transcript variant 3
人 SMTN (NM_001207017) cDNA克隆 transcript variant 4
人 SMTN (NM_001207018) cDNA克隆 transcript variant 5

基因简介

This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2011]

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