人 MSH2 (NM_001258281) cDNA克隆

基本信息

Accession: NM_001258281
基因名称: MSH2
基因别名: FCC1; COCA1; HNPCC; LCFS2; HNPCC1
基因描述: Homo sapiens mutS homolog 2 (MSH2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2607 (查看编码区序列)
翻译后氨基酸长度: 868 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate segment of the first exon, including the translation start site, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G104581 人 MSH2 (NM_001258281) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MSH2 (NM_000251) cDNA克隆 transcript variant 1
人 MSH2 (NM_001258281) cDNA克隆 transcript variant 2

基因简介

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

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