人 CENPA (NM_001809) cDNA克隆

Accession: NM_001809
基因名称: CENPA
基因别名: CenH3; CENP-A
基因描述: Homo sapiens centromere protein A (CENPA), transcript variant 1, mRNA.
种属: Human
CDS区长度: 423 (查看编码区序列)
翻译后氨基酸长度: 140 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
产品编号 产品名称 载体 规格 价格
G104721 人 CENPA (NM_001809) cDNA克隆 pDONR223 2ug质粒 点击询价

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]