人 CREM (NM_182718) cDNA克隆

基本信息

Accession: NM_182718
基因名称: CREM
基因别名: ICER; CREM-2; hCREM-2
基因描述: Homo sapiens cAMP responsive element modulator (CREM), transcript variant 5, mRNA.
种属: Human
CDS区长度: 330 (查看编码区序列)
翻译后氨基酸长度: 109 (查看氨基酸序列)
Transcript Variant: This variant (5), also known as ICER11 gamma and hCREM 2beta-b, uses an alternative downstream promoter, and differs in the 5' UTR and 5' coding region, compared to variant 1. This results in a shorter isoform (5, also known as e) with a distinct N-terminus, compared to isoform 1. This isoform represents one of the early repressor ICER isoforms.

订购信息

产品编号 产品名称 载体 规格 价格
G104853 人 CREM (NM_182718) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CREM (NM_181571) cDNA克隆 transcript variant 1
人 CREM (NM_182723) cDNA克隆 transcript variant 10
人 CREM (NM_182724) cDNA克隆 transcript variant 11
人 CREM (NM_182769) cDNA克隆 transcript variant 13
人 CREM (NM_182770) cDNA克隆 transcript variant 14
人 CREM (NM_182771) cDNA克隆 transcript variant 15
人 CREM (NM_182772) cDNA克隆 transcript variant 16
人 CREM (NM_183013) cDNA克隆 transcript variant 19
人 CREM (NM_001881) cDNA克隆 transcript variant 2
人 CREM (NM_183012) cDNA克隆 transcript variant 20
人 CREM (NM_183011) cDNA克隆 transcript variant 21
人 CREM (NM_183060) cDNA克隆 transcript variant 22
人 CREM (NM_001267562) cDNA克隆 transcript variant 23
人 CREM (NM_001267563) cDNA克隆 transcript variant 24
人 CREM (NM_001267564) cDNA克隆 transcript variant 25
人 CREM (NM_001267565) cDNA克隆 transcript variant 26
人 CREM (NM_001267566) cDNA克隆 transcript variant 27
人 CREM (NM_001267567) cDNA克隆 transcript variant 28
人 CREM (NM_001267568) cDNA克隆 transcript variant 29
人 CREM (NM_001267569) cDNA克隆 transcript variant 30
人 CREM (NM_001267570) cDNA克隆 transcript variant 31
人 CREM (NM_182717) cDNA克隆 transcript variant 4
人 CREM (NM_182718) cDNA克隆 transcript variant 5
人 CREM (NM_182719) cDNA克隆 transcript variant 6
人 CREM (NM_182720) cDNA克隆 transcript variant 7
人 CREM (NM_182721) cDNA克隆 transcript variant 8

基因简介

This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]

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