人 CD247 (NM_000734) cDNA克隆

基本信息

Accession: NM_000734
基因名称: CD247
基因别名: T3Z; CD3H; CD3Q; CD3Z; TCRZ; CD3-ZETA
基因描述: Homo sapiens CD247 molecule (CD247), transcript variant 2, mRNA.
种属: Human
CDS区长度: 492 (查看编码区序列)
翻译后氨基酸长度: 163 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice site in the mid-coding region, which results in a missing in-frame codon, as compared to variant 1. The encoded isoform (2) is thus missing an internal amino acid, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G105081 人 CD247 (NM_000734) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CD247 (NM_198053) cDNA克隆 transcript variant 1
人 CD247 (NM_000734) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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