人 SPP1 (NM_001040058) cDNA克隆

基本信息

Accession: NM_001040058
基因名称: SPP1
基因别名: OPN; BNSP; BSPI; ETA-1
基因描述: Homo sapiens secreted phosphoprotein 1 (SPP1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 945 (查看编码区序列)
翻译后氨基酸长度: 314 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR and coding sequence compared to variant 5. The resulting isoform (OPN-a, as described in PubMed: 7837791) has a shorter and distinct N-terminus compared to isoform e.

订购信息

产品编号 产品名称 载体 规格 价格
G105763 人 SPP1 (NM_001040058) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SPP1 (NM_001040058) cDNA克隆 transcript variant 1
人 SPP1 (NM_000582) cDNA克隆 transcript variant 2
人 SPP1 (NM_001040060) cDNA克隆 transcript variant 3
人 SPP1 (NM_001251829) cDNA克隆 transcript variant 4
人 SPP1 (NM_001251830) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

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