人 SESN3 (NM_001271594) cDNA克隆

基本信息

Accession: NM_001271594
基因名称: SESN3
基因别名: SEST3
基因描述: Homo sapiens sestrin 3 (SESN3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1062 (查看编码区序列)
翻译后氨基酸长度: 353 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice site compared to variant 1. It encodes a shorter protein (isoform 2) compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G105804 人 SESN3 (NM_001271594) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SESN3 (NM_144665) cDNA克隆 transcript variant 1
人 SESN3 (NM_001271594) cDNA克隆 transcript variant 2

基因简介

This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]

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