人 TRIM5 (NM_033092) cDNA克隆

基本信息

Accession: NM_033092
基因名称: TRIM5
基因别名: RNF88; TRIM5alpha
基因描述: Homo sapiens tripartite motif containing 5 (TRIM5), transcript variant gamma, mRNA.
种属: Human
CDS区长度: 1044 (查看编码区序列)
翻译后氨基酸长度: 347 (查看氨基酸序列)
Transcript Variant: This variant (gamma) includes an alternate segment in the 3' coding region, compared to variant alpha, which results in a frameshift. The resulting protein (isoform gamma) has a shorter and distinct C-terminus, compared to isoform alpha.

订购信息

产品编号 产品名称 载体 规格 价格
G106074 人 TRIM5 (NM_033092) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TRIM5 (NM_033034) cDNA克隆 transcript variant alpha
人 TRIM5 (NM_033093) cDNA克隆 transcript variant delta
人 TRIM5 (NM_033092) cDNA克隆 transcript variant gamma

基因简介

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]

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