人 AFF4 (NM_014423) cDNA克隆

Accession: NM_014423
基因名称: AFF4
基因别名: MCEF; AF5Q31
基因描述: Homo sapiens AF4/FMR2 family, member 4 (AFF4), mRNA.
种属: Human
CDS区长度: 3492 (查看编码区序列)
翻译后氨基酸长度: 1163 (查看氨基酸序列)
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G106220 人 AFF4 (NM_014423) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]