人 AFF3 (NM_002285) cDNA克隆

Accession: NM_002285
基因名称: AFF3
基因别名: LAF4; MLLT2-like
基因描述: Homo sapiens AF4/FMR2 family, member 3 (AFF3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3681 (查看编码区序列)
翻译后氨基酸长度: 1226 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the predominantly occurring transcript. It encodes isoform 1.
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G151698 人 AFF3 (NM_002285) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]