This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
人 MAPK13 (NM_002754) cDNA克隆
| Accession: | NM_002754 |
|---|---|
| 基因名称: | MAPK13 |
| 基因别名: | SAPK4; PRKM13; MAPK 13; MAPK-13; p38delta |
| 基因描述: | Homo sapiens mitogen-activated protein kinase 13 (MAPK13), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 1098 (查看编码区序列) |
| 翻译后氨基酸长度: | 365 (查看氨基酸序列) |
| Transcript Variant: | This variant (1) represents the longer transcript and is protein-coding. |
| 人 MAPK13 (NM_002754) cDNA克隆 | transcript variant 1 |
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