人 GABRA2 (NM_001286827) cDNA克隆

基本信息

Accession: NM_001286827
基因名称: GABRA2
基因描述: Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1371 (查看编码区序列)
翻译后氨基酸长度: 456 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate exon in the 5' end and contains an alternate in-frame exon in the 3' end, which leads to the use of a downstream start codon compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus and contains an alternate segment compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G106240 人 GABRA2 (NM_001286827) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GABRA2 (NM_000807) cDNA克隆 transcript variant 1
人 GABRA2 (NM_001114175) cDNA克隆 transcript variant 2
人 GABRA2 (NM_001286827) cDNA克隆 transcript variant 3

基因简介

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

相关产品