人 GMDS (NM_001253846) cDNA克隆

基本信息

Accession: NM_001253846
基因名称: GMDS
基因别名: GMD; SDR3E1
基因描述: Homo sapiens GDP-mannose 4,6-dehydratase (GMDS), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1029 (查看编码区序列)
翻译后氨基酸长度: 342 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G106274 人 GMDS (NM_001253846) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GMDS (NM_001500) cDNA克隆 transcript variant 1
人 GMDS (NM_001253846) cDNA克隆 transcript variant 2

基因简介

GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009]

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