人 SLC18A1 (NM_001142324) cDNA克隆

基本信息

Accession: NM_001142324
基因名称: SLC18A1
基因别名: CGAT; VAT1; VMAT1
基因描述: Homo sapiens solute carrier family 18 (vesicular monoamine transporter), member 1 (SLC18A1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1482 (查看编码区序列)
翻译后氨基酸长度: 493 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1. The resulting isoform (b) has the same N- and C-termini but lacks an internal segment, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G106385 人 SLC18A1 (NM_001142324) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SLC18A1 (NM_001135691) cDNA克隆 transcript variant 1
人 SLC18A1 (NM_003053) cDNA克隆 transcript variant 2
人 SLC18A1 (NM_001142324) cDNA克隆 transcript variant 3
人 SLC18A1 (NM_001142325) cDNA克隆 transcript variant 4

基因简介

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008]

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