人 IKBKG (NM_001099856) cDNA克隆

基本信息

Accession: NM_001099856
基因名称: IKBKG
基因别名: IP; IP1; IP2; FIP3; IPD2; NEMO; FIP-3; Fip3p; AMCBX1; ZC2HC9; IKK-gamma
基因描述: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1464 (查看编码区序列)
翻译后氨基酸长度: 487 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate promoter and initiates translation from an alternate in-frame upstream start codon compared to variant 1. The resulting isoform (b) has a longer N-terminus compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G106559 人 IKBKG (NM_001099856) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IKBKG (NM_001099857) cDNA克隆 transcript variant 1
人 IKBKG (NM_001099856) cDNA克隆 transcript variant 2
人 IKBKG (NM_003639) cDNA克隆 transcript variant 3
人 IKBKG (NM_001145255) cDNA克隆 transcript variant 4

基因简介

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]

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