人 PAICS (NM_001079525) cDNA克隆

Accession: NM_001079525
基因名称: PAICS
基因别名: ADE2; AIRC; PAIS; ADE2H1
基因描述: Homo sapiens phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1299 (查看编码区序列)
翻译后氨基酸长度: 432 (查看氨基酸序列)
Transcript Variant: This variant (1) represents one of the longest transcripts and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G106599 人 PAICS (NM_001079525) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]