人 TUBB3 (NM_001197181) cDNA克隆

Accession: NM_001197181
基因名称: TUBB3
基因别名: CDCBM; TUBB4; CDCBM1; beta-4; CFEOM3A
基因描述: Homo sapiens tubulin, beta 3 class III (TUBB3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1137 (查看编码区序列)
翻译后氨基酸长度: 378 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1.
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G106735 人 TUBB3 (NM_001197181) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]