人 CYP39A1 (NM_001278738) cDNA克隆

Accession: NM_001278738
基因名称: CYP39A1
基因描述: Homo sapiens cytochrome P450, family 39, subfamily A, polypeptide 1 (CYP39A1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1350 (查看编码区序列)
翻译后氨基酸长度: 449 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
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G106801 人 CYP39A1 (NM_001278738) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]