人 CBLC (NM_001130852) cDNA克隆

Accession: NM_001130852
基因名称: CBLC
基因别名: CBL-3; RNF57; CBL-SL
基因描述: Homo sapiens Cbl proto-oncogene C, E3 ubiquitin protein ligase (CBLC), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1287 (查看编码区序列)
翻译后氨基酸长度: 428 (查看氨基酸序列)
Transcript Variant: This variant (2) omits an in-frame coding exon compared to variant 1, resulting in a shorter protein (isoform 2).
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G106812 人 CBLC (NM_001130852) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]