人 HTR3A (NM_001161772) cDNA克隆

基本信息

Accession: NM_001161772
基因名称: HTR3A
基因别名: HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R
基因描述: Homo sapiens 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic (HTR3A), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1392 (查看编码区序列)
翻译后氨基酸长度: 463 (查看氨基酸序列)
Transcript Variant: This variant (3) has an alternate 5' exon and lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (c), that has a different N-terminus and is missing an internal segment compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G106825 人 HTR3A (NM_001161772) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 HTR3A (NM_213621) cDNA克隆 transcript variant 1
人 HTR3A (NM_000869) cDNA克隆 transcript variant 2
人 HTR3A (NM_001161772) cDNA克隆 transcript variant 3

基因简介

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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