人 SNX1 (NM_148955) cDNA克隆

Accession: NM_148955
基因名称: SNX1
基因别名: VPS5; HsT17379
基因描述: Homo sapiens sorting nexin 1 (SNX1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1374 (查看编码区序列)
翻译后氨基酸长度: 457 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame segment of the 5' coding region, compared to variant 1. It encodes a shorter isoform (b), also known as SNX1A, that is missing an internal segment compared to isoform a.
产品编号 产品名称 载体 规格 价格
G106954 人 SNX1 (NM_148955) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]