人 SLC4A8 (NM_001267615) cDNA克隆

Accession: NM_001267615
基因名称: SLC4A8
基因别名: NBC3; NDCBE
基因描述: Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 8 (SLC4A8), transcript variant 7, mRNA.
种属: Human
CDS区长度: 1917 (查看编码区序列)
翻译后氨基酸长度: 638 (查看氨基酸序列)
Transcript Variant: This variant (7) has an alternate first exon and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (f) is shorter at the N-terminus and has a shorter and distinct C-terminus compared to isoform a.
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G107249 人 SLC4A8 (NM_001267615) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]