人 ACSS2 (NM_001076552) cDNA克隆

Accession: NM_001076552
基因名称: ACSS2
基因别名: ACS; ACSA; ACAS2; ACECS; dJ1161H23.1
基因描述: Homo sapiens acyl-CoA synthetase short-chain family member 2 (ACSS2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2145 (查看编码区序列)
翻译后氨基酸长度: 714 (查看氨基酸序列)
Transcript Variant: This variant (2) includes an alternate in-frame exon in the central coding region, compared to variant 1, resulting in a longer isoform (2), compared to isoform 1.
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G107275 人 ACSS2 (NM_001076552) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]