人 GLRX (NM_001118890) cDNA克隆

基本信息

Accession: NM_001118890
基因名称: GLRX
基因别名: GRX; GRX1
基因描述: Homo sapiens glutaredoxin (thioltransferase) (GLRX), transcript variant 2, mRNA.
种属: Human
CDS区长度: 321 (查看编码区序列)
翻译后氨基酸长度: 106 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 3' UTR, compared to variant 1. Variants 1-4 encode the same protein.

订购信息

产品编号 产品名称 载体 规格 价格
G107416 人 GLRX (NM_001118890) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GLRX (NM_002064) cDNA克隆 transcript variant 1
人 GLRX (NM_001118890) cDNA克隆 transcript variant 2
人 GLRX (NM_001243658) cDNA克隆 transcript variant 3
人 GLRX (NM_001243659) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]

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