人 FOXP1 (NM_001244810) cDNA克隆

基本信息

Accession: NM_001244810
基因名称: FOXP1
基因别名: QRF1; 12CC4; hFKH1B; HSPC215
基因描述: Homo sapiens forkhead box P1 (FOXP1), transcript variant 4, mRNA.
种属: Human
CDS区长度: 2082 (查看编码区序列)
翻译后氨基酸长度: 693 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate in-frame exon but contains another compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is longer compared to isoform 1. This variant encodes the longest isoform, which has been shown to enhance embryonic stem (ES) cell pluripotency and repress ES cell differentiation.

订购信息

产品编号 产品名称 载体 规格 价格
G107471 人 FOXP1 (NM_001244810) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 FOXP1 (NM_032682) cDNA克隆 transcript variant 1
人 FOXP1 (NM_001012505) cDNA克隆 transcript variant 2
人 FOXP1 (NM_001244808) cDNA克隆 transcript variant 3
人 FOXP1 (NM_001244810) cDNA克隆 transcript variant 4
人 FOXP1 (NM_001244812) cDNA克隆 transcript variant 5
人 FOXP1 (NM_001244813) cDNA克隆 transcript variant 6
人 FOXP1 (NM_001244814) cDNA克隆 transcript variant 7
人 FOXP1 (NM_001244815) cDNA克隆 transcript variant 8
人 FOXP1 (NM_001244816) cDNA克隆 transcript variant 9

基因简介

This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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