人 KRAS (NM_033360) cDNA克隆

基本信息

Accession: NM_033360
基因名称: KRAS
基因别名: NS; NS3; CFC2; KRAS1; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B
基因描述: Homo sapiens Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant a, mRNA.
种属: Human
CDS区长度: 570 (查看编码区序列)
翻译后氨基酸长度: 189 (查看氨基酸序列)
Transcript Variant: This variant (a) is composed of six exons, including exon 4a, which the shorter transcript variant (b) lacks. This rare variant (a) has a cds that terminates in exon 4a and encodes a unique C-terminus, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G107994 人 KRAS (NM_033360) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 KRAS (NM_033360) cDNA克隆 transcript variant a
人 KRAS (NM_004985) cDNA克隆 transcript variant b

基因简介

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]

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